WebThe human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid cytoplasmic domain. Recombinant soluble human BCMA is a 50 amino acid polypeptide (5.3kDa) comprising the TNFR homologous region of the BCMA protein. WebKaggle Human Protein Altas(1/26~5/11). Contribute to Human-Protein-Atlas-Team/Human-Protein-Atlas development by creating an account on GitHub.
The Human Protein Atlas
WebBCMA1-Fc fusion protein was also constructed, purified and analyzed by indirect and competitive ELISA. Results: The binding rates of BCMA1-Fc for BAFF were 91.7%, but 80.6% for mAPRIL, suggesting that BCMA1-Fc without BCMA2, bound BAFF well and less efficiently to mAPRIL. Conclusion: WebThe Human Protein Atlas was initiated in 2003 with the aim of mapping all human proteins within cells, tissues, and organs and providing this information in an open-access format … gym exercises to burn leg fat
B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell ...
WebBCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell … WebMar 2, 2024 · B-cell maturation antigen (BCMA, TNFRSF17) is a confirmed cell surface target for MM. BCMA is expressed on malignant plasma cells from patients with MM, with normal tissue expression limited primarily to plasma cells and a subset of activated B cells. 18 Multiple BCMAxCD3 bsAbs and anti-BCMA CAR T cells are being tested in the clinic … WebFeb 10, 2024 · BCMA is a non–tyrosine kinase receptor surface glycoprotein that is widely expressed on malignant plasma cells and most MM cell lines as well [ 5 ]. BCMA by its ligand, APRIL, increases survival and long-lived plasma cells that contribute to MM development. It is closely related to the BAFF receptor (BAFF-R), that highly expresses … boys tracksuit bottoms sports direct